
PT-141
Dosage10mg
Rp 990.000per vial
Cold-chain delivery to your door around Bali. Pens and bacteriostatic water available, just ask.
- Class
- Melanocortin receptor agonist
- Half-life
- 2-3 hours
Also known as Bremelanotide, Vyleesi
Tested in large, late-stage human trials, but not an approved medicine.
FDA approved as Vyleesi for HSDD in women; male use for ED is off-label.
About this peptide
PT-141 (bremelanotide) comes at sex drive from a different angle to pills like Viagra and Cialis. Those work mainly on the physical side, on blood flow, while PT-141 works higher up, on arousal and desire in the brain. That is why it is studied for cases where libido has dropped off, not just the mechanics. Supplied as a freeze-dried powder for research use.
What it does
Research subjects report stronger desire and more intense orgasms within a couple of hours of a dose. It draws the most interest from men rebuilding their sex drive after a steroid cycle, women whose desire has dropped off, and anyone the standard erection pills haven't been enough for.
What to expect
Week 1
The first few doses can take six to eight hours to kick in while the pathway wakes up.
Weeks 2-4
Once it is established, most people feel it within one to two hours of dosing.
Weeks 4-12
This is where dosing frequency matters. Occasional use stays clean, but daily or near-daily use is where the skin-darkening and muddy-tan reports show up.
Long term
With ongoing use it is worth keeping an eye on moles and skin, since these receptors touch pigment.
A rough guide drawn from research and community reports. Individual results vary and nothing here is a promise.
Reported effects
Reported benefits
Side effects & cautions
Key points
Best suited to research into low desire rather than a purely mechanical problem. Worth being clear-eyed about the trade-offs: nausea is very common, blood pressure rises briefly, and frequent dosing can darken skin over time.
It activates melanocortin receptors in the brain, mainly MC3 and MC4, the switches that drive sexual arousal. It was built to leave the MC1 receptor alone, the one that controls skin pigment, but at higher or more frequent doses some crossover happens, which is where the skin-darkening reports come from.
Nausea is the big one and very common, because the same receptors sit in the gut. Expect a short-lived bump in blood pressure and some facial flushing too. Skin darkening can happen with frequent use, but it is dose-driven rather than guaranteed, more on that below. It should be avoided by anyone with uncontrolled high blood pressure or existing heart disease.
Supplied as a freeze-dried powder for research use. Reconstitute with bacteriostatic water, adding it slowly down the inside wall of the vial rather than directly onto the powder, and swirl gently rather than shaking to avoid foaming and protect the peptide. Refrigerate after reconstitution. Administration is subcutaneous or nasal. We do not offer or recommend intravenous use.
- Blood pressure
- Transient increases in blood pressure
- Heart rate
- Transient increases in heart rate
What studies and users commonly report happening to these markers. Research context only, not medical advice.
Questions about PT-141
The usual pills like Viagra and Cialis work mainly on blood flow, the physical side. PT-141 works higher up, in the brain, on arousal and desire more directly. That is why it draws interest for cases where the blood-flow pills aren't enough on their own.
It is very common, because the same receptors it works on also sit throughout the gut. The gap between a good dose and a queasy one is narrow, so higher doses tend to bring more nausea.
Yes, but it is dose-driven. At the intended occasional use it is uncommon, around 1 percent. Taken daily it becomes likely, about 38 percent in an eight-day daily study, and it does not always reverse. Spaced out, it is rarely an issue.
Yes, they are cousins. PT-141 and Melanotan are both melanocortin peptides, which is why heavy PT-141 use can tan or darken skin the way Melanotan does. Used occasionally and spaced out, PT-141 rarely causes it; Melanotan is the one people take specifically for pigment.
Evidence
Sourcing
Sourced carefully from vetted suppliers. Where a Certificate of Analysis is available we share it on request, and we'll always tell you what we have for your batch.
For Research Use Only
Sold strictly for laboratory and research purposes. Not for human or veterinary use, not a medicine, and not for diagnostic or therapeutic application.